THE ENDO-METABOLIC SYNDROME – by: Dr. James Villarreal

THE ENDO-METABOLIC SYNDROME – by: Dr. James Villarreal


Effects of leptin and the dys-regulation in overweight patients.

Obesity can be cured. Yes, treatment has been available for years and more recognized since 2006, in the US.  The good news is that treatment is safe, inexpensive, and predictable.  For those who suffer from the disease – state of obesity, weight reduction methods are better than ever. Surgeries, lipo-suction, and other life-risk procedures are not required anymore. The proof is abundant and even endorsed by well-respected medical professionals and leaders.

With a connection made between the appetite-based form of obesity and other metabolic problems suffered by most chronically overweight persons, solutions became clear and predictable.

The hypothalamus, center of appetite regulation, was identified as a source of problems for many obese people.  The connections between that gland and the inter-dependence of the other endocrine glands offered a view into the delicate exchanges which occur between them and the balance necessary to regulate metabolism, correctly.

Most everyone understands the cause of diabetes, type II, and can see the corrective therapies at work with the “regulation” of insulin. What was not so clear, was the effects of leptin, the hormone secreted by the hypothalamus. Thanks to pioneering physicians like Dr. A.T.Q. Simeons, that uncertainty has become more clear and leptin’s influence on weight related problems.

Leptin illustrationA new idea that leptin was irregular in obesity (persons’ with obesity) created tactical therapy wherein that condition was manipulated by a clinical process, effectively.  Re-regulation of leptin allowed patients to beat their condition or at least gave them a chance to correct other metabolic failures in their bodies, leading to systematic recovery.  A protocol that controlled macro-nutrients, e.g., carbohydrates, fat specifically, calories, and used medication to support healthy hypothalamic function, created a breakthrough for the obese.

The dys-regulation of leptin and insulin creates a complex series of metabolic failures and immense inflammatory conditions (Joel B. Klein, M.D.)  Resensitizing patients’ to leptin and insulin has virtually extinguished their weight related problems and reversed diabetic conditions, within 6 weeks.  The down-line of positive adjustments for that patient has been monumental, with noted shifts in blood work, reductions and elimination of features, and the patients’ reports of recovery.

Critics of the Dr. Simeons Protocol believe there is not a clear connection made between hypothalamic dys-regulation and someone’s ability to lose body fat specific to that claim.  In other words, anyone can lose weight from a low calorie diet. However, critics have been unable to disprove the claims and cannot dispute the visible evidence provided by many thousands of patients.


Recently, the HCG Protocol received praise and acknowledgement by the First Lady Michelle Obama in her speech to Americans about controlling the obesity epidemic.  But soon after, the media yanked the commercial down.  Other celebrity professionals like Dr. OZ from TV., have given favorable mention to the HCG Weight Loss Protocol. There are many types of medical weight loss programs.  B 12 MIC Lipotropics is a healthy B rich cocktail that helps patients. There are others.


Not everyone needs HCG or medications to manage their weight, there are many other approaches and products which work well.  Most clinical experts agree that a low-glycemic diet, proper nutrition, exercise, and good supplementation remain a formula for health for many others.

High carbohydrate diet causes

Normal hormonal responses to

manage the glucose loads from

the meal.


Because of the dual problem with high Caloric intake, excessive secretion of leptin (hypothalamus) and insulin, a dondition escalates creating “insensitivity” and disease, e.g., diabetes II and obesity.


Leptin has not been typically

controlled or manipulated in

medical environs and the puzzle

chronic appetite-driven obesity has



Clinical management of leptin, insulin and other key hormones, the obese condition

can be extinguished. Patients can self-regulate and adhere to a healthy program optimizing their health.


The great thing is that great choices provided by experts can restore health, vitality and self-confidence to all.

Anyone suffering from irregular weight control problems should consider a full physical examination and blood draw with a qualified expert.  Hormone regulation may be necessary to help you complete the transition from poor health to great health.

Hormones like estrogen, progesterone, cortisol, testosterone all play a vital role in well-being and longevity.  Hormone Replacement Therapy (HRT) is safe, effective, and restores vitality and energy; it is truly a reversal of age-related conditions.

Men who suffer from middle-aged maladies can get proper treatment with testosterone replacement and youth restoring aesthetic treatments, taking years off.  Metabolism requires attention and at times a “tune-up”.  So, today’s medical advancements can allow all of us to enjoy a higher quality of life.

Dr. James Villarreal